Zika virus NS5

[Zika virus non-structural protein 5] abbr. ZIKV NS5. This non-structural protein is encoded in the genome of Zika virus. Zika virus NS5 embeds an S-adenosyl-L-methionine-dependent methyltransferase (hence the terms Zika Virus Methyltransferase; Zika Virus NS5 Methyltransferase, Zika Virus MTase). This transferase is involved in viral 5'-RNA capping, which protects the viral genome and is essential for viral replication (Egloff MP et al, 2002; Coutard B et al, 2017). Like conserved NS5 proteins from other flaviviruses, Zika virus NS5 also contains a protein domain with the function of a C-terminal RNA-dependent RNA-polymerase (Zika virus NS5 Polymerase); also: Zika virus NS5 methyl-transferase polymerase ... ... ... ...
 
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Entry last modified: April 2022