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Yaba monkey tumor virus 2L protein

abbr. YMTV-2L. 2L protein. This protein is a TNF binding protein encoded in the genome of Yaba monkey tumor virus (Yaba monkey tumor virus TNF binding protein). The protein binds human and monkey TNF with high affinity and rabbit TNF with only low affinity. YMTV-2L inhibits human TNF-mediated signaling in cells (affinity for human TNF: KD = 440 pM; for monkey TNF: KD = 230 pM). This binding protein is distinct from viral TNF receptor homologs ... ... ... ... ... Subscribe to continue reading! ... ...

 

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