Varicella zoster virus ORF8 protein |
Varicella zoster virus ORF63 |
prominin-2 |
||
ORF61, encoded by an open reading frame in the genome of Varicella zoster virus is an immediate early gene expressed during infection with Varicella zoster virus. The protein down-regulates the stimulation of viral putative immediate-early, early, and late promoters by other viral trans-activator genes (Nagpal S and Ostrove, 1991). ORF61 can trans-activate or trans-repress the transcription of other viral proteins, including its own promoter, to enhance infectivity (Moriuchi et al, 1993, 1994; Wang et al, 2009; Perera et al, 1992). Zhu et al (2011) have reported that overexpression of ORF61 has only a minor effect on Sendai virus-induced NF-kappa-B signalling. ORF61 interacts with phosphorylated IRF3 and induces degradation of the protein, thereby preventing IFN-beta expression. The ORF61 protein contains an N-terminal RING domain
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R