Vaccinia virus K1 protein |
Vaccinia virus K7R protein |
Pleurocidin 09 |
||
[Vaccinia virus K7R protein] This protein is encoded in the genome of Vaccinia virus and has been identified by Schröder et al (2008). Vaccinia virus K7 protein can inhibit IFN-beta induction in response to pattern recognition receptor activation by preventing IRF3 activation mediated by TBK1 / IKK-epsilon. DDX3 [DEAD box protein 3] has been identified as a critical host target of the viral protein involved in this process. Vaccinia virus K7 protein expression inhibited the activation of NF-kappa-B in response to IL1 and NF-kappa-B activation induced by TLR4 and TLR3. The viral protein also inhibits NF-kappa-B-dependent expression of the chemokine IL8
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R