VLA4 receptor alpha 4 subunit |
VLA-5-alpha |
Pelophylaxin-2GY |
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[very late activation antigen 5] Very late activation antigens are a family of heterodimeric transmembrane proteins that belong to the integrin family of cell adhesion molecules (Hynes, 1987; Ruoslahti, 1991). These antigens consist of a distinct alpha subunit non-covalently linked to a common beta subunit. Their name refers to the observation that beta-chains increase in amount and additional alpha-subunits appear after long-term T-cell activation (Hemler et al, 1987).
Based on its identity with ITGA5 [integrin-alpha-5], VLA-5 is being referred to also as VLA-alpha 5 [very late activation antigen alpha-5]. VLA-5 has been identified independently as GPIc [
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