Urocortin-1 neurons |
Urocortin-2 neurons |
HPKRWIL |
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abbr. UCN2 (UCNII) Older designations for Urocortin-2 are URP [urocortin-related peptide] or SRP [stresscopin-related peptide] (Hsu and Hsueh, 2001). Human Urocortin-2 (IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC) is related to Urocortin-1 and belongs to a protein family that also has corticotropin releasing factor as its member. The protein has been identified by Hsu and Hsue (2001) as a high-affinity ligand for CRHR2, a receptor for corticotropin releasing hormone. The gene encoding this peptide
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