tumor growth factor-beta-1 |
tumor homing peptides |
Mgrp |
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abbr. TGIF (a term with multiple meanings).
This biochemically uncharacterized factor of approximately 43 kDa is secreted by peripheral blood mononuclear cells activated by a preparation of streptococci (OK-432). The factor inhibits the growth of the human stomach carcinoma cell line MK-1 and is cytostatic for seven out of ten human tumor cell lines tested. A combination of suboptimal concentrations of this factor and IFN-gamma also inhibit the growth of these cells.
The activity of TGIF cannot be blocked by antibodies directed against human IFN or TNF
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