thrombospondin type 3 repeats |
Thrombostatin con-3 |
IL12R-beta-2 |
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Thrombostatin con-1 [QPWSQCSATCGDGVRERRR] is a bioactive fragment (see also: cryptides) corresponding to positions 347-365 of THSD1 [thrombospondin type I domain containing 1] [THSD1(347-365)], a gene of unknown function that is known in databanks also as TMTSP [Transmembrane molecule with thrombospondin module]. The peptide fragment has been shown to inhibit the proliferation and migration of human umbilical vein endothelial cells in vitro and is therefore thought to possess anti-angiogenic properties in vivo (Karagiannis and Popel, 2008).
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