Th3 T-cells |
Th5 helper cells |
Neural-endocrine-immune system |
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[Th5 cell, Th5]
[T-helper 5 cells; Th5 helper cells; Th5 T-cells] These cells constitute a subpopulation of T-helper cells described by Kurowska-Stolarska et al (2008). These cells produce mainly IL5, but not IL4, both of which are characteristic type 2 cytokines produced by Th2 T-helper cells.
Th5 cells are generated from murine and human naive CD4(+) T-cells by IL33 in the presence of antigen. This polarization requires the IL1 receptor-related receptor ST2
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