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Tal-1

[Tal-1(+), Tal-1(-), SCL(+), SCL-)]

[T-cell acute lymphocytic leukemia 1] This tissue-specific basic helix-loop-helix transcription factor has been identified by Finger et al (1989) as a transcriptional unit designated TCL5 [T-cell leukemia/lymphoma 5] at the site of a chromosomal translocation in a lymphohemopoietic stem cell line derived from a patient with acute T-lymphoblastic leukemia. Begley et al (1989, 1991) have used the term SCL [stem cell leukemia hematopoietic transcription factor] for the transcription factor identified in a leukemic stem cell line that has the ability to differentiate into myeloid cells or ... ... ... ... ... Subscribe to continue reading! ... ...

 

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