TSP2 |
TSP86/84 |
Membrane-associated phosphatidylinositol transfer protein 3 |
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[tumor-specific protein 180; tumor surface protein 180] TSP-180 has been identified as a tumor-associated glycoprotein complex on the surface of several murine lung carcinomas (Kennel, 1979; Kennel et al, 1980). TSP-180 shows preferential expression in diverse malignant carcinomas from mice (Kennel et al, 1986) and humans (Falcioni et al, 1988). There is a correlation between TSP-180 expression and the malignant potential of some tumor types in mice (Falcioni et al, 1987). Sacchi et al (1989) have reported that a monoclonal antibody (MoAb 135-13C) to TSP-180 stimulates tumor cell growth in vitro.
Kennel et al (1989) have identified TSP-180 as the integrin integrin-alpha-6 (CD49f) / integrin-beta-4 (CD104
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