Tiggywinkle hedgehog |
TIGIRR-2 |
SHP substrate 1 |
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[three immunoglobulin domain-containing IL1 receptor-related-1] This protein has been identified together with TIGIRR-2 (see: IL1RAPL) by Born et al (2000). The proteinis identical with IL1RAPL2 [IL1 receptor accessory protein-like-2]. A databank synonym of this protein is IL1R9 [Interleukin-1 receptor 9].
The protein is a member of the IL1 receptor protein family and contains a cytoplasmic domain resembling other IUL1 receptor proteins. However, engagement of this receptor or of chimeric IL1 receptors containing the TIGIRR-1 cytoplasmic domain with IL1-alpha, IL1-beta
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