TIE-1 |
TIE2-expressing monocytes |
TAC2 |
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[tyrosine kinase with immunoglobulin and EGF homology domains-2]. Another designation in the nomenbclature of CD antigens is CD202. The complex extracellular domain of this receptor contains 2 immunoglobulin-like loops separated by 3 copies of an EGF-like repeat that are connected to 3 fibronectin type 3-like repeats. The receptor has been described also as TEK [tunica endothelial kinase]. The human TEK gene maps to chromosome 1p34-p33 (Partanen et al, 1992).
In rats, mice, and humans this receptor-like tyrosine kinase, called also TEK, is expressed almost exclusively in the
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