TFPI-1 |
TFPI-alpha |
Nr1 |
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[tissue factor pathway inhibitor-2] This Kunitz-type serine protease inhibitor protein is related to TFPI-1 (tissue factor pathway inhibitor-1). It is known also as MSPI [matrix-associated serine protease inhibitor]. The protein is identical with PP5 [placental protein 5] identified originally as a heparin binding placental glycoprotein inhibiting plasmin, trypsin, and thrombin (Bützow et al, 1988; Kisiel et al, 1994). Tanaka et al (2004) state that PP5 is identical with REF-1 [RPE cell factor, retinal pigment epithelial cell factor-1]. For a bioactive fragment of TFPI-2 see also: EDC34.
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