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TC22 peptide

This peptide (MTVVLLLIVLPLLGGVHSSGIL) from the beetle Tribolium castaneum shows activity as an anticancer peptide and inhibits the growth and viability of HeLa cells and MCF-7 breast cancer cells. TC22 peptide induces cell death by apoptosis in HeLa cells and activates caspase-9 and caspase-3. It also promotes the generation of reactive oxygen species and triggers expression of p53 (Liu et al, 2019)

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