Surfactant protein G |
Surfactant pulmonary-associated D-binding protein |
Microglobulin-beta-2 |
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abbr. SP-H [Surfactant-associated protein H; surfactant associated 3]. The protein is being referred to also as SFTPH. The approved gene symbol for this protein is SFTA3 [Surfactant-associated protein 3]. The protein has no sequence or structural identity to other surfactant proteins.
This protein (Schicht et al, 2014) is secreted by lung alveolar type 2 pneumocytes in response to lipopolysaccharide. IL1-beta and IL23 inhibit the expression. Diler et al (2014) have reported that Surfactant protein H markedly increases phagocytosis in vitro in the murine-derived alveolar macrophage cell lines
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