stress hematopoiesis |
Stress-Induced Chondrocytic 1 |
melanocyte-stimulating hormone release inhibiting hormone |
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[stress response-specific peptide inhibitor 1] Stressin with the sequence LPPLPYP (Leu-Pro-Pro-Leu-Pro-Tyr-Pro) is a synthetic peptide based on structural mimicry to a functional domain of p53, a key factor in the responses of cells to stressful stimuli.
The peptide has been shown to prevent excessive cell loss induced by cell stress. The peptide inhibits both cell death by apoptosis and the secretion of inflammatory mediators by fibroblasts and macrophages
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