Staphylococcus aureus Efb |
Staphylococcus aureus Emp |
Arginase-2 |
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[Efb homologous protein] ehp is a secreted protein of Staphylococcus aureus identified by Hammel et al (2007). The protein is a virulence factor and plays a role in immune response evasion.
The mature Ehp polypeptide is composed of 80 residues and is 44 % identical to the complement inhibitory domain of Efb [Extracellular fibrinogen-binding protein]. Ehp binds preferentially to native and hydrolyzed C3 relative to fully active C3b. Ehp potently inhibites C3b deposition onto sensitized surfaces by the alternative complement activation pathway.
For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary
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