Staphylococcus aureus clumping factors

these factors are produced by Staphylococcus aureus and play a role as virulence factors and immune responsion evasion factors. Two clumping factors, designated ClfA [clumping factor A] and ClfB [clumping factor B] have been identified (McDevitt D et al, 1994, 1995; Nı́ Eidhin D et al, 1998). In contrast to ClfA, which is present on cells at all stages of the growth cycle, ClfB is present only at a detectable and functional level on the surface of cells of strain Newman in the exponential phase of growth (Nı́ Eidhin D et al, 1998).

Both factors are related surface-associated proteins that bind fibrinogen. ClfA ... ... ... ...
 
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Entry last modified: November 2010