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Staphylococcus aureus Ecb

[Extracellular complement-binding protein] Ecb has been identified by Jangerius et al (2007). Ecb plays a role in immune response evasion has strong anti-inflammatory properties and blocks C5 convertase activity and prevents C5a generation and C5a-mediated neutrophil activation in vitro. Ecb blocks C5a-dependent neutrophil recruitment into the peritoneal cavity in a mouse model of immune complex peritonitis. The strong anti-inflammatory properties (Jongerius et al, 2007). Jangerius et al (2010) have shown that Ecb binds to the C3d domain of C3 and thereby blocks C3 convertases of the alternative pathway and C5 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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