spätzle-5 |
SPACE peptide |
deltaHER2 |
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symbol: spe. This Drosophila melanogaster serine protease is encoded by gene CG16705. The enzyme has been identified by Jang et al (2006). Spätzle processing enzyme generates the active ligand form of the cytokine Spätzle. Spätzle processing enzyme is expressed in immune tissues and is important for the activation of the Toll receptor by Spätzle in innate immunity (Mulinari et al, 2006).
Flies with reduced Spätzle processing enzyme expression show no noticeable processing of the inactive proform of Spätzle
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