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Sf-caspase-1

[Spodoptera frugiperda caspase-1] This enzyme is a member of a family of evolutionarily conserved cysteine protease proteins known as caspases. Many of these enzymes are part of a proteolytic cascade that plays a central role in cell death by apoptosis. Sf-caspase-1 is a caspase found in Spodoptera frugiperda, the natural host of baculoviruses.

Sf-caspase-1 is highly related to human MCH3 and CPP32 in sequence and specific activity. Sf-caspase-1 is produced as a proenzyme (zymogen) of 299 amino acids that can is processed autocatalytically to an active enzyme heterocomplex consisting of a large p19/p18 and a small p12 subunit (Ahmad et al, 1997). However, activation of the ... ... ... ... ... Subscribe to continue reading! ... ...

 

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