scolopendrasin VII |
Scolopin-1 |
PDCD7 |
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Scolopendrasin X, MKKFHCLKKICKGLCAKLamide is an antimicrobial peptide from the centipede Scolopendra subspinipes mutilans. Scolopendrasin X strongly stimulates mouse neutrophils, resulting in intracellular calcium increase, chemotactic migration, and increased superoxide anion production. The activities are mediated through the FPR2 receptor. Scolopendrasin X significantly blocks inflammatory cytokine production induced by lipopolysaccharide in mouse neutrophils.
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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