SECTM1B |
seele |
PGC7 |
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[secreted EGF repeat and discoidin domains containing protein 1] The mouse gene encoding this protein has been identified by Ensslin and Shur (2003) in a testis cDNA library. The encoded protein localizes to the Golgi complex of differentiating spermatogenic cells. The protein is secreted by epididymal cells and adheres to the sperm cell plasma membrane. The protein binds specifically to the zona pellucida of unfertilized oocytes, but not to the zona of fertilized eggs.
Sequence analysis shows that this protein is the mouse counterpart of MFGE8 [Milk fat globule epidermal growth factor-8].
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