SDGF |
SDGF(38-80) |
pHLIP variant 7 |
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[spleen-derived growth factor-3] This factor has been isolated as a heparin binding mitogen (see also: HBGF [heparin binding growth factors]) for rat hepatocytes from bovine spleen (Suzuki et al, 1993). SDGF-3 is also mitogenic for mouse epidermal keratinocytes but not for mouse fibroblasts.
The mitogenic activity of SDGF-3 is abolished by a neutralizing monoclonal antibody specific for KGF (keratinocyte growth factor) and it is believed that this bovine spleen-derived mitogen for hepatocytes and
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