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SDF-2

[stromal cell-derived factor-2] This factor of unknown function was isolated from the mouse stromal cell line ST2, by the signal sequence trap method. SDF-2 is a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %. The human SDF-2 gene maps to chromosome 17q11.2.

Significantly low levels of SDF-2 are seen in patients with poor clinical outcome when compared with patients who remained disease-free (Kang et al, 2009).

See also: SDF-1.

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