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SARS coronavirus non-structural protein-1

This protein is encoded in the genome of SARS coronavirus. Law et al (2007) have shown this protein plays an important role in the expression of the chemokines CCL5, CXCL10, and CCL3 in human lung epithelial cells via the activation of NF-kappa-B.

For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.

For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary section of this encyclopedia.

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