S100A12 |
S100A14 |
TAM motif |
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[S100 calcium binding protein A13] The gene (human chromosome 1q21) encodes a calcium-binding protein of 98 amino acids related to the S100 family of proteins (Wicki et al, 1996). The protein is expressed at high levels in a wide variety of human tissues (Ridinger et al, 2000).
S100A13 has been shown to play a role in the secretion of several proteins that lacks an N-terminal signal sequence and therefore are secreted by a non-classical pathway independent of the ER-Golgi pathway.
aFGF is released as a heteromeric complex containing the p40 extravesicular domain of p65
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