Rinderpest virus V protein

This nonstructural protein is encoded by Rinderpest virus (RPV), a paramyxovirus closely related to the human pathogen Measles virus. The protein is a virulence factor as its deletion causes specific defects in growth and transcription of viral RNAs (Baron and Barrett, 2000). The protein contributes to immune evasion. It binds to the signal transducer STAT1 and prevents the action of both type 1 interferon (IFN-alpha) and type 2 interferon (IFN-gamma) (Nanda and Baron, 2006).

For other relevant entries see also the Pathogenicity/Virulence Factors Dictionary section of this encyclopedia.

For other proteins/peptides with functions in innate immunity ... ... ... ...
 
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Entry last modified: July 2015