Resolvin E1
abbr. RvE1. Resolvin E1 [5S,12R,18R-trihydroxy-eicosapentaenoic acid; 5S,12R,18R)-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid; 5,12,18R-trihydroxy-EPA] is an enzymatically oxygenated product of eicosapentaenoic acid, one of the main dietary essential omega-3 polyunsaturated fatty acids (Serhan et al, 2000; Arita et al, 2005).
Resolvin E1 belongs to a class of compounds termed resolvins [resolution-phase interaction products], which are generated during inflammation and microbial infections. In the presence of aspirin, Resolvin E1 is formed from eicosapentaenoic acid via cell-cell interactions involving cells bearing cyclooxygenase-2
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