RNF147 |
RNF162B |
Serum paraoxonase/arylesterase 2 |
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[RING finger protein 152] RNF152 is a protein containing a RING finger domain. Zhang et al (2010) have reported that the protein has E3 ligase activity. It is polyubiqitinated partly through Lys-48-linked ubiquitin chains in vivo. RNF152 is localized in lysosomes and co-localizes with LAMP-3. The protein is associated with lysosome-related cell death by apoptosis. Over-expression of RNF152 in Hela cells induces cell death by apoptosis.
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
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