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RINm5F

An established rat insulinoma cell line. The cells have been used, among other things, to develop a bioassay for IL1. The cells respond to murine and human IL1-beta and IL1-alpha in the range of 0.1 to 1 unit/mL to produce nitric oxide.

Nitric oxide formation is not induced by IL2, IL4, IL6, IL9, IL11, IL15, TNF-alpha, IFN-gamma, and bacterial lipopolysaccharides either alone or in combination and these cytokines do not significantly potentiate or attenuate the response to ... ... ... ... ... Subscribe to continue reading! ... ...

 

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