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RAW117-P cell proliferation inhibitor

This factor, also termed liver-derived tumor cell growth inhibitor, is found in the conditioned medium of murine and rat livers. It has been isolated also from extracts of human liver (Cavanaugh and Nicolson, 2000).

The factor inhibits the growth of human KM12SM colon carcinoma cells and murine RAW117-P large-cell lymphoma cells and is less active on the variant subline RAW117-H10. RAW117-H10 cells are highly liver-metastasizing while RAW117-P cells are not.

The factor inhibits the growth of many cells at high concentration but is more potent on cells ... ... ... ... ... Subscribe to continue reading! ... ...

 

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