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RAS cells

[Respiratory Airway Secretory cells] this distinct cell type has been found in human distal airways. These secretory cells are cuboidal in shape and constitute an abundant cell type in human respiratory bronchioles, where they are interspersed between alveolar type 1 cells and alveolar type 2 cells. The cells express SCGB3A2 [secretoglobin family 3A member 2] and CD66c and are distinct from cells in larger proximal airways. Organoid modelling reveals that RAS cells act as unidirectional progenitors for alveolar type 2 cells. RAS cell lineage ... ... ... ...
 
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Entry last modified: June 2022



 
 
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