Piwi-interacting RNAs
[Piwi-interacting RNA]
abbr. piRNAs [P-element-induced wimpy testis-interacting small RNAs] These small non-coding RNAs of 26-31 nucleotides constitute the largest class small non-coding RNAs (Aravin et al, 2006; Kirino and Mourelatos, 2006); conservative estimates in some reviews put their numbers to 20,000-100,000. piRNAs are slightly longer than microRNAs and small interfering RNAs.
Piwi-interacting RNAs were identified originally in Drosophila melanogaster and termed rasiRNAs [repeat associated small interfering RNAs] (Aravin et al, 2003). These RNAs were renamed
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