Pierisin-2 |
Pierisin-4 |
ADAM metallopeptidase domain 9 |
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The cDNA for this protein has been cloned from gray-veined white, Pieris melete, butterfly (Yamamoto M et al, 2009). Pierisin-3 shows 93 % similarity with Pierisin-1 (for related proteins see also: Pierisin-2, Pierisin-4, Pierisin-5, Pierisin-6). The recombinant protein has activities of an anticancer peptide and causes cell death by apoptosis in human cervical carcinoma HeLa cells and human gastric carcinoma TMK-1 cells. The protein binds DNA
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