PMN-derived lymphocyte proliferation-potentiating factor |
Pmng1 |
A1-activator |
||
[polymorphonuclear leukocyte-derived lymphocyte proliferation-potentiating factor] This factor of 18.5 kDa is released by rabbit early inflammatory peritoneal exudate cells (98 % of polymorphonuclear leukocytes, PMN) stimulated with kaolin. It augments proliferation in a comitogenic assay with thymocytes.
Rabbit PMN factor and human IL1-beta are considered homologous. This conclusion is based on its physicochemical properties and the known aminoterminal amino acid sequence (Goto et al, 1988).
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