PLGLB1 |
PLIN2 |
MSMP |
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[placenta immunomodulatory ferritin] PLIF is a subunit variant of the ubiquitous iron storage protein Ferritin. PLIF consists of the ferritin heavy chain sequence in which the 65 C-terminal amino acids are substituted with a cytokine-like 48 amino acid domain, designated C48. In contrast to the heavy chain of Ferritin, PLIF mRNA does not include the iron response element in the 5'-untranslated region, suggesting that PLIF synthesis is not regulated by iron (Moroz et al, 2002). PLIF has been identified independently as an immunoregulatory protein termed p43-PLF [p43 placenta isoferritin].
PLIF protein has been found to localize in
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