PF-382 inhibitory factor |
PF[4-241] |
cathepsin G-like-2 |
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This biochemically uncharacterized factor is secreted into the conditioned medium of PF-382 cells, a human T-cell line obtained from pleural effusions of a child with T-acute lymphoblastic leukemia (Pegoraro et al, 1985; Bellone et al, 1988). The factor, which is different from IL1, IL3, IL4, GM-CSF and G-CSF, is a potent enhancer of BFU-E growth but is inactive on CFU-GM (see also: hematopoiesis). The activity of this factor synergizes with an activity conditioned medium obtained from monocytes.
PF-382 cells
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