PD-1 |
PD-1-beta |
40 kDa keratin |
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[Phosphodiesterase-1/nucleotide pyrophosphatase] also: PDI-alpha. The gene encoding this enzyme of 863 amino acids has been cloned from rat brain by Narita et al (1994). Kawagoe et al (1995) have cloned the human cDNA. Human and rat protein show 89 % identity. Another designation for the gene is PDNP2 [phosphodiesterase nucleotide pyrophosphatase-2].
The enzyme is identical with Autotaxin. PD-1-alpha lacks 52 amino acids of autotaxin and both proteins are most likely splice variants (Kawagoe et al, 1995).
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