OCN |
OCT |
ADAM metallopeptidase domain 15 |
||
[osteoclast colony stimulating factor] This biochemically uncharacterized factor of 17 kDa is secreted by murine mammary carcinoma cells (Lee et al, 1991). Conditioned medium from a tumor clone (CESJ cells) grown under serum-free conditions has been shown to contain O-CSF.
It causes marked bone resorption in animals and stimulates the clonal growth of primitive osteoclast progenitors from BMC (bone marrow culture) (Hayase et al, 1997).
See also: CSF for a general treatment of colony stimulating factors.
... ... ... ... ... Subscribe to continue reading! ... ...
Content view restricted ! |