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Neutrophil-derived Giant Phagocytes

[Neutrophil-derived Giant Phagocyte]

The term Giant Phagocytes has been given to a cell type developing in long-term cultures of purified CD15(+) CD66b(+) CD63(+) neutrophils in standard culture conditions without the addition of cytokines / growth factors such as GM-CSF / IL4 (Dyugovskaya L et al, 2014). The cells exhibit a neutrophilic phenotype and are CD11b(+) CD15(+) / CD63(+) / MPO(+) / CD66b(+) and express neutrophil elastase. They show phagocytosis of neutrophil ... ... ... ... ... Subscribe to continue reading! ... ...

 

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