NACHT domain

an acronym standing for NAIP (neuronal apoptosis inhibitor protein), C2TA (MHC class II transcription activator), HET-E (incompatibility locus protein from Podospora anserina) and TP1 (telomerase-associated protein) (Koonin and Aravind, 2000).

This domain is a putative nucleotide-binding domain (nucleoside triphosphatase domain) and has been found together with other domains (such as PAAD, DAPIN, HEAT, CARD domain, WD domain, BIR domain, LRR) in a variety of proteins that are involved in the regulation of inflammation ... ... ... ...
 
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Entry last modified: January 2016