metaphyseal dysplasia without hypotrichosis |
Metargidin |
KRS2 |
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[MPV G Glycoprotein] Metapneumovirus (hMPV) is a paramyxovirus (van den Hoogen et al, 2001), which has been linked to acute respiratory illness in children, the elderly and the immunocompromised (Boivin et al, 2002, 2003). G Glycoprotein encoded by this virus is a polymorphic type 2 mucin-like glycoprotein (Peret et al, 2004). Unlike G glycoproteins from related viruses such as HRSV [human respiratory syncytial virus] (Tripp et al, 2001) and APV [avian metapneumovirus type C] (Alvarez et al, 2003), metapneumovirus G Glycoprotein does not contain a CX3C motif that mediates chemokine mimicry (Tripp et al, 2001) (see also: glycoprotein G).
Bao et al (2008) have identified G Glycoprotein as a virulence factor that inhibits the production of important immune and antiviral mediators. Airway
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