Macrophage-derived cytotoxic factor |
Macrophage-derived endothelial cell inhibitor |
Bone-derived growth factor-1.7 |
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abbr. MDF (a term with multiple meanings). This biochemically uncharacterized factor (3 and 11 kDa) is released by granuloma-like lesions of mice (giant and epithelioid macrophages). The factor strongly inhibits production of superoxide anions in mouse, guinea pig, human, macrophages and mouse neutrophils activated with Phorbol esters, all-transretinal, or fMet-Leu-Phe.
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