Muteins |
mv |
neglect-induced death |
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This continuous leukemia cell line has been established from a patient with acute myeloid leukemia. MUTZ-8 cells express mainly markers of myeloid cells but also some markers of monocytes and megakaryocytes. It does not express markers of T-cells, B-cells and erythroid cells (see also: hematopoiesis). MUTZ-8 displays a deletion of the 5q31 AML/MDS region (see also: 5q minus syndrome).
The cells require external cytokines for growth (see also: factor-dependent cell lines). Some cytokines stimulate growth while others are growth-inhibitory.
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