M(Hb) macrophages |
MHC augmenting factor |
veil cells |
||
[MHC augmenting factor] This factor of 35 kDa was isolated from the conditioned medium of Concanavalin A-activated human peripheral blood mononuclear cells (Puri and Saxena, 1998).
MHC AF augments the expression of major histocompatibility complex 1 antigens on K562 and gastric carcinoma tumor (HR) cells.
The effect of MHC AF is not observed with IFN-alpha, IFN-beta, TNF, IL2, IL4, IL5 and IL7. IFN-gamma shows significant MHC AF activity and the activity is partially blocked by antibodies against IFN-gamma.
Purified MHC AF preparations do not have any activity in WISH
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |