MCFD2 |
MCFS-1 |
autophagy/beclin-1 regulator 1 |
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This activity (approximately 50 kDa, pI ~5) is produced constitutively by a T-cell line, STO-5. MCF-pl5-L is a lactose-binding protein. It has no affinity for heparin. It is chemotactic for monocytes and alveolar macrophages but not for eosinophils or neutrophils. The factor can prolong the life span of alveolar macrophages, probably by inhibiting cell death by apoptosis. It also stimulates production of TNF-alpha from macrophages (Yamanaka et al, 2000).
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