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MATH domain

[MATH domains]

[meprin and TRAF homology domain; meprin and TRAF-C homology domain]; also: TD domain or TRAF domain [TNF-receptor associated factor domain] or TRAF/MATH domain. This domain of approximately 180 amino acids is found in cytosolic signaling molecules such as members of the TRAF family of proteins, which interact with TNF receptors, and in meprins, which are functionally unrelated mammalian tissue-specific extracellular zinc endopeptidases (Sunnerhagen et al, 2002; Uren and Vaux, 1996).

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