Laminet-1 |
laminin-1 |
Gly-Val-Phe-Thr-Gln-Gly-Ala-His-Gly-Ser-Tyr-Pro-Arg-Valamide |
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abbr. Lmnt2. Laminet-2 has been identified as a cell surface glycoprotein resembling both laminins and netrins (hence the designation Laminet) (Yin et al, 2002). Sequence analysis shows that laminet-2 is identical with netrin-G2.
Laminet-2 is expressed selectively in neurons. The distribution pattern of Laminet-2 differs from that of the related Laminet-1. Both proteins are expressed in distinct non-overlapping cell populations. Laminet-2 proteins is subject to alternative splicing. The splice isoforms contain a unique combination of potential binding sites for ligands or counterreceptors.
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